R. Martin Arthur

Newton R. and Sarah Louisa Glasgow Wilson Professor of Engineering


Office: 2120D Green Hall
Tel. (314) 935-6167
email: rma@ese.wustl.edu
     

Education
Univ. of Pennsylvania
Ph.D. 1968
Rice University
B.A., B.S., M.S. 1962, 1963,1964

Interim Chair
 2002-2005

Research & Teaching
Ultrasonic Imaging
Electrocardiography
Signal & Image Processing

Memberships
IEEE
American Heart Association
American Institute for Ultrasound in Medicine
International Society for Computerized Electrocardiology
Sigma Xi
Sigma Tau
Tau Beta Pi

 

 
Following postdoctoral work from 1969 to 1970, Professor Arthur joined the faculty at Washington University, where he is now a Professor of Electrical and Systems Engineering and a Professor of Biomedical Engineering.

Studies carried out by Professor Arthur in collaboration with cardiologists at the Washington University School of Medicine are aimed at identifying adults who have had a heart attack and are at increased risk of having a subsequent attack. Even when these patients' hearts are beating normally, there are changes in their electrocardiograms that indicate they are at increased risk of developing a new life-threatening arrhythmia. Professor Arthur and his colleagues have identified subtle changes that occur in the spatial distribution, spectral characteristics, as well as in the waveforms of the electrocardiograms from patients at risk. Risk of arrhythmia occurrence is determined from the analysis of torso shape and from the nature and distribution of body-surface electrocardiograms.

In another series of studies, one aimed at improving ultrasonic techniques for the detection and staging of cancer, Professor Arthur has devised synthetic-focus algorithms for medical ultrasonic imaging. In contrast to conventional imaging methods, these ellipsoidal-backprojection algorithms permit images produced by an array of transducers to be in focus at each picture element. Adaptive-focus techniques are being developed to improve image focus and simultaneously extract a velocity map of the tissue being imaged. In a joint effort, Professors Arthur and William D. Richard are developing special-purpose computer architectures to support real-time ellipsoidal backprojection imaging. This imaging system will use massive parallelism and will be based on custom CMOS VLSI circuits currently under development.

Professor Arthur is a fellow of the American Institute for Medical and Biological Engineering. He was a member of the Committee on the Safe Use of Electricity in Health Care Facilities of the National Fire Protection Association, which writes the National Electric Code for hospitals. He has presented short-course tutorials on the safe use of electricity in hospitals. He was a member of the Editorial Committee of the Annual Reviews of Biophysics and Bioengineering and a member of the Editorial Board of the Journal of Clinical Engineering.

 
     

Undergraduate Research

&

Graduate Independent Study

 

 
     

Selected Publications
 


R. M. Arthur
, "Errors in Forward and Inverse Electrocardiography from Reducing a Full-Body Surface to a Torso Model", Medical & Biological Engineering & Computing, in review.  <abstract>

D. Basu, R. M. Arthur, Y. Guo and J. W. Trobaugh, "3D Temperature Imaging during Non-Uniform Heating using Ultrasonic Backscattered Energy", IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, in review. <abstract>

R. M. Arthur, C. D. Holmes and Weiyuan Zhao, "Real-Time Ultrasonic Thermometry Based on the Change in Backscattered Energy", 31st Society for Thermal Medicine Meeting, Minneapolis, MN, 6-10 May 2014. <abstract> <pdf>

R. M. Arthur, J. W. Trobaugh, Y. Guo, and B. Zhao, "Signal-to-noise improvement in ultrasonic thermometry based on the change in backscattered energy", 38th International Symposium on Ultrasonic Imaging and Tissue Characterization, Washington, D.C., 10-12 June 2013.
Ultrasonic Imaging, vol. 35, pp. 247 (abstract), 2013.<abstract>

J. I. Laughner, F. S. Ng, M. S. Sulkin, R. M. Arthur and I. R. Efimov, "Processing and analysis of cardiac optical mapping data obtained with potentiometric dyes,"  Am J Physiol: Heart Circ Physiol,  303:H753-H765, 2012. <abstract>

R. M. Arthur, Y. Lin, S. Wang and J. W. Trobaugh, "Effects of Action Potential Duration on the Electrocardiogram in Type II Diabetes", International Journal of Bioelectromagnetism, December 2012.  http://ijbem.k.hosei.ac.jp/2006-/volume14/number3/ijbem_vol14_no3_pp141-153.pdf <abstract>

R. M. Arthur, "Temperature Imaging Using Ultrasound", chapter 13 in Physics Of Thermal Therapy, Fundamentals and Clinical Applications, Editor: E. G. Moros, Series: Imaging In Medical Diagnosis And Therapy (William R. Hendee, Series Editor), Taylor & Francis, 2012. <abstract>

R. M. Arthur and JW Trobaugh, "Electrocardiographic Textbooks Based on Template Hearts Warped using Ultrasonic Images", IEEE Transactions on Biomedical Engineering, in press, 2012.<abstract>
http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=6224173

R. M. Arthur
, S. Wang, and J. W. Trobaugh, "Changes in Body-Surface Electrocardiograms from Geometric Remodeling due to Obesity", IEEE Transactions on Biomedical Engineering, vol. 58, no.6, pp. 1565-1573, 2011. <abstract>

R. M. Arthur
, D. Basu, Y. Guo, J. W. Trobaugh, and E. Moros, "3D In Vitro Estimation of Temperature Using the Change in Backscattered Ultrasonic Energy, IEEE Trans. on UFFC, vol. 57, no. 8, pp. 1724-1733, 2010. <abstract>

R. M. Arthur, D. Basu, Y. Guo, J. W. Trobaugh, W. L. Straube and E. G. Moros, "Temperature Imaging during NonUniform Tissue Heating with Ultrasonic Backscatter Energy using Self-Calibration", 35th International Symposium on Ultrasonic Imaging and Tissue Characterization, Washington, D.C., 17-19 May 2010. <abstract>
Ultrasonic Imaging, vol. 32, pp. 281-282 (abstract), 2010.

S. Wang and R. M. Arthur, "A New Method for Estimating Cardiac Transmembrane Potentials from the Body Surface", International Journal of Bioelectromagnetism, vol. 11, no. 1, pp. 59 - 63, 2009. <pdf>

R. M. Arthur, S. Wang, and J. W. Trobaugh, "Changes in Body-Surface Electrocardiograms from
Geometric Remodeling due to Obesity", International Journal of Bioelectromagnetism, vol. 11, no. 1, pp. 46 - 49, 2009. <pdf>

Y. Guo, J. W. Trobaugh, and R. M. Arthur, "A Framework for Temperature Imaging using the Change in Backscattered Ultrasonic Signals", 34th International Symposium on Ultrasonic Imaging and Tissue Characterization, Washington, D.C., 10-12 June 2009. <abstract>
Ultrasonic Imaging, vol. 31, pp. 74-75 (abstract), 2009.

D. Basu, R. M. Arthur, J. W. Trobaugh, Y. Guo, W. L. Straube, "3D Temperature Imaging using Change in Ultrasonic Backscattered Energy: Estimation of Temperature during Non-Uniform Heating", 34nd International Symposium on Ultrasonic Imaging and Tissue Characterization, Washington, D.C., 10-12 June 2009. <abstract>
Ultrasonic Imaging, vol. 31, pp. 75-77 (abstract), 2009.

R. M. Arthur, W. L. Straube, J. W. Trobaugh, and E. G. Moros, "In vivo change in ultrasonic backscattered energy with temperature in motion-compensated images" Int. J. Hyperthermia, Vol. 24, No. 5, pp 389–398, 2008. <abstract>

J. W. Trobaugh, R. M. Arthur, W. L. Straube and E. G. Moros "A Simulation Model for Ultrasonic Temperature Imaging Using Change in Backscattered Energy", Ultrasound in Medicine & Biology, Vol. 34, No. 2, pp. 289–298, 2008. <abstract>

Shuli Wang, R. M. Arthur and J. W. Trobaugh, "Body-Surface Electrocardiography Variations Caused by Changes in Cardiac Geometry Due to Diabetes and Obesity", Memphis Biomedical Imaging Symposium 2007, Memphis, Tennessee, 1-2 November 2007. <abstract><poster>

Debomita Basu, R. M. Arthur and J. W. Trobaugh, "Role of Collagen in the Temperature Dependence of Ultrasonic Backscatter", Memphis Biomedical Imaging Symposium 2007, Memphis, Tennessee, 1-2 November 2007. <abstract><poster>

Yuzheng Guo, Jason W. Trobaugh and R. M. Arthur, "Motion Compensation for Temperature Imaging using the Change in Ultrasonic Backscattered Energy", Memphis Biomedical Imaging Symposium 2007, Memphis, Tennessee, 1-2 November 2007.<abstract><poster>

R. M. Arthur, J. W. Trobaugh, Y. Guo, W. L. Straube,  and E. G. Moros, "Change in Ultrasonic Backscattered Energy for Temperature Imaging: Factors Affecting Temperature Accuracy and Spatial Resolution", 32nd International Symposium on Ultrasonic Imaging and Tissue Characterization, Washington, D.C., 16 May 2007.<abstract><pdf>
Ultrasonic Imaging, vol. 29, pp. 47-48 (abstract), 2007.

W. L. Straube , R. M. Arthur and J. W. Trobaugh, "Noninvasive Temperature Monitoring Using Change in Backscattered Energy for Clinically Relevant Heating Scenarios", World Conference on Interventional Oncology and Society of Thermal Medicine, 2007 Joint Annual Meeting, Washington, D.C., May 16, 2007.<abstract><pdf>

R. M. Arthur, J. W. Trobaugh, W. L. Straube and E. G. Moros, "Developing Ultrasonic Temperature Imaging to Aid Cancer Treatment" SPIE Newsroom, http://spie.org/x8432.xml, 2007.

R. M. Arthur, J. W. Trobaugh, W. L. Straube J. Parry, Y. Guo and E. G. Moros, "Change in Ultrasonic Backscattered Energy for Temperature Imaging:  Simulation Studies with Multiple Scatterers and Measurements from In Vivo Images", 31st International Symposium on Ultrasonic Imaging and Tissue Characterization, Washington, D.C., 24 May 2006.<abstract><pdf>
Ultrasonic Imaging, vol. 28, pp. 4-5 (abstract), 2006.

W. L. Straube, R. M. Arthur,  J. W. Trobaugh, J. Parry, Y. Guo and E. G. Moros, "In Vivo Measurement of Changes in Ultrasonic Backscattered Energy for Homogeneous (Water Bath) and Heterogeneous (SAHUS) Heating" Proceedings 2006 Annual Meeting of the Society for Thermal Heating, Bethesda, MD, 6-8 April 2006, p. 39. <abstract><pdf>

R. M.
Arthur, W. L. Straube, J. W. Trobaugh, J. Parry, Y. Guo and E. G. Moros, "In Vivo Change in Ultrasonic Backscattered Energy with Temperature in Motion-Compensated Images", 2006 Annual Convention, American Institute for Ultrasound in Medicine, Washington DC, 26 March 2006.<abstract><pdf>
J of Ultrasound in Med, vol. 25, pp. S75 (abstract), 2006.

R. M. Arthur, J. W. Trobaugh, W. L. Straube and E. G. Moros, "Temperature Dependence of Ultrasonic Backscattered Energy in Motion-Compensated Images", IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, vol. 52, pp. 1644-1652, 2005. <abstract><pdf>

R. M. Arthur, W. L. Straube, J. W. Trobaugh, and E. G. Moros, "Noninvasive Estimation of Hyperthermia Temperatures with Ultrasound", International Journal of Hyperthermia, vol. 21, pp. 589-600, 2005.<abstract> <pdf>

R. M. Arthur, W. L. Straube, J. W. Trobaugh, and E. G. Moros, "Recent Advances In Ultrasonic Temperature Imaging Using Changes In Backscattered Ultrasound", 22nd European Society for Hyperthermic Oncology, Graz, Austria, June, 2005. <abstract><pdf>

W.L. Straube, J. Parry, E. Moros, J. Trobaugh, and R.M. Arthur, "An In Vivo System for the Determination of the Effect of Temperature on Backscattered Ultrasound Energy in Ultrasonic Images",  Society for Thermal Medicine, Bethesda, Maryland, April 1-3, 2005. <abstract><poster>

J. W. Trobaugh and R. M. Arthur, "Estimation of Surface Pose with a Physically-Based Ultrasonic Image Model", IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, vol. 51, pp. 1128-1136, 2004. <abstract> <website>

D. G. Beetner and R. M. Arthur, "Estimation of Heart-Surface Potentials Using Regularized Multipole Sources", IEEE Transactions on Biomedical Engineering, vol. 51, pp. 1366-1373, 2004. <abstract><pdf>

R. M. Arthur, J. W. Trobaugh, W. L. Straube and E. G. Moros, "3D Temperature Dependence of Ultrasonic Backscattered Energy in Images Compensated for Apparent Tissue Motion", 9th International Congress on Hyperthermic Oncology, St. Louis, April, 2004. <abstract> <poster>

J. W. Trobaugh, R. M. Arthur, W. L. Straube and E. G. Moros, "Effects of scatterer populations on temperature dependence of backscattered ultrasonic energy ", Poster, 9th International Congress on Hyperthermic Oncology, St. Louis, April, 2004. <abstract> <poster>

M. E. Cain, R. M. Arthur and J. W. Trobaugh, "Detection of the Fingerprint of the Electrophysiological Abnormalities the Increase Vulnerability to Life-Threatening Ventricular Arrhythmias", J. of Interventional Cardiac Electrophysiology, vol. 9, pp. 103-118, 2003. <abstract>

R. M. Arthur, J. W. Trobaugh, W. L. Straube, E.G. Moros and S. Sangkatumvong , "Temperature Dependence of Ultrasonic Backscattered in Images Compensated for Tissue Motion", Proceedings of the 2003 International IEEE Ultrasonics Symposium", Honolulu, Hawaii, October 5-8, 2003. <abstract>

J. W. Trobaugh, W. L. Straube, R. M. Arthur, E. G. Moros and S. Sangkatumvong, "Apparent Motion and Temperature Dependence of Backscattered Energy in Ultrasonic Images", Poster, 21st Annual Meeting of the North American Hyperthermia Society, Quebec City, Canada, September 10-14, 2003. <abstract> <poster>

R. M. Arthur, W. L. Straube, J. D. Starman and E. G. Moros, "Noninvasive Temperature Estimation Based on the Energy of Backscattered Ultrasound," Medical Physics, vol. 30, pp. 1021-1029, 2003. <abstract>

J. W. Trobaugh and R. M. Arthur, "Methods for Using Ultrasound to Generate a Heart Surface for Electrocardiographic Inverse Problems", International Journal of Bioelectromagnetism, vol. 5, pp. 314-315, 2003. <abstract> <journal>

R. M. Arthur, K. J. Timbadia, A. Rauf and J. W. Trobaugh, "Effects of Reducing the Full-Body Surface to a Torso Model in Forward and Inverse Electrocardiography", International Journal of
Bioelectromagnetism, vol. 5, pp. 312-313, 2003. <abstract> <journal>

W. L. Straube, R. M. Arthur, J. D. Starman, and E. G. Moros, "The Effect of Temperature Change on Backscattered Ultrasound Power," Poster, 44th American Association of Physicists in Medicine Meeting, Montreal, Canada, 16 July 2002. <abstract> <poster>

R. M. Arthur, W. L. Straube and E. G. Moros, "Noninvasive Temperature Estimation Based on the Energy of Backscattered Ultrasound", Invited Talk, 20th Annual Meeting of the North American Hyperthermia Society, Reno, Nevada, 20 April, 2002. <abstract> <talk>

W. L. Straube, R. M. Arthur, J. D. Starman, and E. G. Moros, "In Vitro Measurement and Analysis of Backscattered Ultrasound and Its Change With Temperature",  Poster, 20th Annual Meeting of the North American Hyperthermia Society (NAHS), Reno, Nevada, 22 April 2002. <abstract> <poster>

R. M. Arthur, W. L. Straube, J. D. Starman and E. G. Moros, "Estimation of Hyperthemic Temperatures from Backscattered Ultrasonic Energy", 19th Annual Meeting of the North American Hyperthermia Society, San Juan, Puerto Rico, April 2001. <abstract>

J. W. Trobaugh and R. M. Arthur, "Representation of Shape in Ultrasonic Images with a Physically-Based Image Model", Proceedings of the IEEE Workshop on Mathematical Methods in Biomedical Image Analysis (MMBIA 2001), pp. 79-86, 2001. <abstract>

J. W. Trobaugh and R. M. Arthur, "A Physically-Based, Probabilistic Model for Ultrasonic Images Incorporating Shape, Microstructure and System Characteristics", IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, vol. 48, pp. 1594-1605, 2001. <abstract> <website>

J. W. Trobaugh and R. M. Arthur, "Registration of the Spine Using a Physically-Based Image Model for Ultrasound", Proceedings of MICCAI 2000, Utrecht, Netherlands, pp. 1176-1177, 2001. <abstract>

R. M. Arthur, "Representation of Tissue for Pulse-Echo Estimation of Speed of Ultrasound," Donald L. Snyder Workshop, Washington University in St. Louis, Springer-Verlag, in press, 2000. <abstract>

M. A. Franklin, A. Mahajan and R. M. Arthur, "Parallel Implementations of 3D Synthetic-Focus Ultrasonic Image Generation using MPI", Proceedings of the Thirteenth ISCA International Conference on Parallel and Distributed Computing Systems, vol. 2, pp. 205-212, 2000. <abstract>

J. W. Trobaugh and R. M. Arthur, "A Discrete-Scatterer Model for Ultrasonic Images of Rough Surfaces," IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, vol. 47, pp. 1520-1529, 2000. <abstract> <website>

M. A. Franklin, A. Mahajan, and R. M. Arthur, "Parallel Implementation of an Ultrasonic Image Generation Algorithm using MPI", Proceedings of the Eleventh IASTED International Conference on Parallel and Distributed Computing and Systems, vol. 2, pp. 589-596, 1999.

Beetner, D. G., and R. M. Arthur, "Direct Inference of the Spectra of Pericardial Potentials Using the Boundary-Element Method," Annals of Biomedical Engineering, vol. 27, pp. 498-507, 1999. <abstract>

R. M. Arthur, "Spherical-Harmonic Approximation to the Forward-Problem of Electrocariology," J. of Electrocardiology, vol. 32, pp. 22-33, 1999. <abstract> <pdf>

R. M. Arthur, D. G. Beetner, H. D. Ambos, M. E. Cain, "Improved Estimation of Pericardial Potentials From Body-Surface Maps Using Individualized Torso Models," J. of Electrocardiology, vol. 31 Supplement, pp. 106-113, 1999. <abstract> <website>

J. Hyttinen, R. M. Arthur, P. Kauppinen, J. Malmivuo, "Parallel Processing Approach for Finite Difference Modelling of Human Thorax as a Volume Conductor," Proceedings of the Engineering in Medicine and Biology Conference 1997, 1998. <abstract>

M. E. Cain, H. D. Ambos, R. M. Arthur, and B. D. Lindsay, "Signal-Averaged Electrocardiography: Methods of Analysis and Clinical Impact," Cardiology, Parmley and Chatterjee editors, Lippincott, New York, chapter 26, pp. 1-36, 1996.

D. G. Beetner, H. D. Ambos, M. E. Cain, and R. M. Arthur, "Determination of Epicarcial Potentials Using Aimed Leads," Medical & Biological Engineering & Computing, vol. 34, suppl. 1, part 2, pp. 97-98, 1996. <abstract> <poster>

D. G. Beetner, and R. M. Arthur, "Generation of Synthetic-Focus Images from Pluse-Echo Ultrasound Using Difference Equations", IEEE Transactions on Medical Imaging, vol. 15, pp. 665-672, 1996. <abstract>

M. E. Cain, H. D. Ambos, N. G. Kavesh, and R. M. Arthur, "Signal-Averaged Electrocardiography," The Heart, Update I, R.A. O'Rourke editor, McGraw-Hill, New York, pp. 41-66, 1996.

R. M. Arthur, N. G. Kavesh, H. D. Ambos, and M. E. Cain, "Phase and Group-Delay Characteristics of Signal-Averaged Electrocardiograms form Patients with Ventricular Tachycardia," IEEE Transactions on Biomedical Engineering, vol. 42, pp. 29-41, 1995. <abstract> <poster>

R. M. Arthur, N. G. Kavesh, H. D. Ambos, and M. E. Cain, "Spectral Analysis of the Cardiac Cycle of Signal-Averaged Frank Leads from Patients with Ventricular Tachycardia," J. of Electrocardiology, vol. 27 Supplement, pp. 218-227, 1994. <abstract>

W. L. Straube and R. M. Arthur, "The Temperature Dependence of Backscattered Ultrasonic Power Normalized for Use in Hyperthermia," Utrasound in Medicine and Biology, vol. 20, pp. 915-922, 1994. <abstract> <poster>